Origin of plasma cell-free DNA after solid organ transplantation.
نویسندگان
چکیده
Transplantation, Yanni Y.N. Lui, Kam-Sang Woo, Angela Y.M. Wang, Chung-Kwong Yeung, Philip K.T. Li, Elaine Chau, Peter Ruygrok, and Y.M. Dennis Lo (Departments of 1 Chemical Pathology, 2 Medicine & Therapeutics, and 3 Surgery, The Chinese University of Hong Kong, Prince of Wales Hospital, Shatin, New Territories, Hong Kong SAR; 4 Department of Cardiology, Grantham Hospital, Hong Kong SAR; 5 Department of Cardiology, Green Lane Hospital, Auckland 1003, New Zealand; * address correspondence to this author at: Department of Chemical Pathology, The Chinese University of Hong Kong, Prince of Wales Hospital, Shatin, New Territories, Hong Kong SAR; fax 852-2194-6171, e-mail [email protected])
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and kidneys account for only a minority of the plasma cell-free DNA. To investigate whether organ transplantation was associated with a quantitative aberration in the concentrations of circulating DNA, we compared total plasma DNA concentrations in the transplant patients and the 10 healthy controls. The median DNA concentrations of the controls and the patients studied were 916.4 and 1336.3 ge...
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ورودعنوان ژورنال:
- Clinical chemistry
دوره 49 3 شماره
صفحات -
تاریخ انتشار 2003